Tuberculosis blood test quantiferon

Tuberculosis (TB) is a contagious disease caused by the Tuberculosis blood test quantiferon bacterium Mycobacterium tuberculosis, which usually infects the lungs but may also extend to any part of the body, including the kidneys, spine and brain. TB, if not treated properly, it may fatal.1 TB bacteria usually spreads through the air by respiratory droplets when a person with respiratory tuberculosis sneezes or coughs, the other, closely proximity.1,2


What is QuantiFERON-TB Gold In-Tube?
An alternative to the tuberculin skin test (TST)

Tuberculosis blood test quantiferon

QuantiFERON-TB Gold In-Tube (QFT-G) is a blood test for use as an aid in the diagnosis of infection with Mycobacterium tuberculosis (both latent TB infection and active tuberculosis) 0.3 ‘test approved by the United States Food and Drug Administration (FDA) for use with adult patients.
The doses of interferon-gamma (IGRA release) are tools for the diagnosis of latent tuberculosis infection (LTBI). These are surrogate markers of infection with Mycobacterium tuberculosis and show a cellular immune response to M. tuberculosis. IGRAs can not distinguish between latent infection and tuberculosis (TB) disease, and should not be used alone for the diagnosis of active tuberculosis, a microbiological diagnosis. A positive IGRA does not necessarily mean active tuberculosis, but a negative IGRA precludes both the active and latent tuberculosis.
In 2001, the QuantiFERON-TB (QFT) (Cellestis manufactured by Limited, Carnegie, Victoria, Australia) has been approved by the Food and Drug Administration (FDA) to help detect latent Mycobacterium tuberculosis infection (1). This test is an aid in the diagnosis in vitro measuring a component of cell-mediated immune response to M. tuberculosis. The test is based on quantification of interferon-gamma (IFN-gamma-interferon) released by sensitized whole blood was incubated overnight with purified protein derivative (PPD) of M. tuberculosis antigens and control lymphocytes.

Tuberculin skin test (TST) has been used for years as an aid in the diagnosis of latent tuberculosis infection (LTBI) and includes the measurement of delayed type hypersensitivity response 48 to -72 hours after intradermal injection of PPD . TST and QFT do not measure the same components of the immune response and are not interchangeable. To assess the accuracy of these tests is limited by the Tuberculosis blood test quantiferon lack of a standard to confirm the lira.

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