Tuberculosis blood test false positive

Latent tuberculosis infection (LTBI) is a non-communicable disease that Tuberculosis blood test false positive remains asymptomatic for many years in individuals and can progress to TB disease. The main purpose of the diagnosis of latent tuberculosis is considered a medical treatment for the prevention of disease in active tuberculosis.

Until recently, the tuberculin skin test (TST) was the only method available for the diagnosis of latent tuberculosis. Unfortunately, the TST is a subjective test can be false positive for those who have been vaccinated with Bacillus Calmette-Guérin (BCG), are infected with mycobacteria other than Mycobacterium tuberculosis complex, or due to other factors, such as reading palpitations Error numerical testing.

Tuberculosis blood test false positive

You have been told by your doctor or medical service of his employer that his tuberculosis (TB) is positive. What does that mean? Do you have TB? Colleagues and family are at risk because they have been around you? If you are on medication? All these are natural reactions to this report.
Tuberculosis is a serious infection that is usually found in the lungs, but can be anywhere on the body. However, it is also possible that the positive test was the result of underlying TB germs have the potential pathogen Mycobacterium tuberculosis (MTB), the agent of tuberculosis. Active TB is the interaction between the invading multipliers TB germ tissue destructive and the host immune system. However, the TB test generally does not mean a disease.
The diagnosis of latent tuberculosis infection (LTBI) is based on host T cell response to antigens of Mycobacterium tuberculosis. Historically, the tuberculin skin test (TST) has been used, but more recently, in vitro assays of interferon gamma (IFN-?) release (IGRA) have become more frequent. IGRAs are based on the measurement of IFN-? released primarily by CD4 + T cells following stimulation with M. tuberculosis specific antigens (2). It is the QuantiFERON-TB Gold tube test (QFT-GIT) (Cellestis Limited, Carnegie, Victoria, Australia) An IGRA is increasingly being used to monitor healthcare latent tuberculosis employees in the United States. Blood is collected in tubes 3 specially designed for the QFT-GIT-that contain antigens from M. tuberculosis antigen (TB [TB Ag] tube), mitogen or antigen, or tuberculosis or mitogen (tube zero). After incubation, the concentration of IFN-? in the plasma of any tube TB Ag tube, and the tube is determined by the mitogen enzyme linked immunosorbent assay (ELISA). The response of tuberculosis is calculated by subtracting the zero TB Ag tube (TB Ag-zero). Tuberculosis blood test false positive The threshold for a positive test is a response to the TB Ag-nil to 0.35 IU / ml

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