Symptoms of primary tb infection

Tuberculosis is an infectious Symptoms of primary tb infection disease caused by Mycobacterium tuberculosis organism. There may be various organs of the body, including the brain, to affect renal and bone; but most commonly affects the lungs (pulmonary TB).

The first stage of the infection usually lasts for several months. During this time natural defenses (immune system) are resistant to the disease, and most or all bacteria. By a fibrous capsule, which underpins developed around Before the first attack is over, some bacteria can escape into the bloodstream and into the body, which in turn are also enriched, carried out in many cases, the disease is not develop beyond this stage -. And it is called TB infection. When the immune system and the infection is not treated to stop, the disease progresses to the second stage, active disease. It multiplies the seed rapidly and destroys the lung tissue (or other affected organ). In some cases, the disease, but it is stopped at the first after a latency period, carbon. Sometimes the latency period of several years, and the bacteria are activated when the opportunity arises, especially when immunity is low.

Symptoms of primary tb infection

If M. tuberculosis is the first (primary infection), lung macrophages engulf host organisms and lead to lymph nodes in the hilum in an attempt to control the infection. Some organisms can spread through the lymphatic or blood to distant sites. Small granulomas (nodules) formed around the body to contain mycobacteria. These may heal spontaneously and bacteria (in 80% of cases) eliminated [2] or encapsulated bacteria in a defensive barrier, but remain in healthy people where the disease as inactive. Only a small proportion of patients, open the progress of tuberculosis (active).
The classic symptoms of an active TB infection are a chronic cough with bloody sputum, fever, night sweats, and weight loss (the last gift of the origin of the common long-term consumption above). Infection of other organs, causes a variety of symptoms. The diagnosis of tuberculosis is on radiology (commonly chest X-rays) and a microscopic examination and microbiological culture of bodily fluids. The diagnosis of latent tuberculosis is on the tuberculin skin (TCT) and / or blood tests test. Treatment is difficult and requires the administration of several antibiotics for a long period of time. Social contacts are also examined and treated if necessary. Antibiotic resistance is a growing problem in multi-drug resistant (MDR-TB) tuberculosis. Prevention relies on screening programs and vaccination Symptoms of primary tb infection with Bacillus Calmette-Guerin.

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