Mantoux Test

Mantoux test – The Mantoux test (or Mantoux test , test sensitivity to tuberculin , Pirquet test , or PPD test (for English  :  Purified Protein Derivative  : Purified Protein Derivative) is a diagnostic tool for TB Mantoux test is used. the United States and is recommended by the American Thoracic Society and the Centers for Disease Control and Prevention ( CDC ). multiple puncture tests such as the Tine test is not recommended. Mantoux test is one of two main skin tests to tuberculin used worldwide to test for tuberculosis . Until 2005, the Heaf test was used in the UK but it has been replaced by the Mantoux test.

The test was announced in 1890 by Robert Koch . It is named after Charles Mantoux , a French physician who devised in 1907 from the work of Koch and Clemens von Pirquet .

A standard dose of 5 tuberculin units ( 0.1 ml ) 1 is injected under the skin and a reading of the result 48 to 72 hours later. It is expected that a person has been exposed to the bacteria showed an immune response of the skin.

The reaction is read by measuring the diameter of induration (cured palpable area) across the forearm (perpendicular to the long axis) in millimeters. The absence of induration should be marked ”  0 mm  “. Erythema (redness) should then be measured.

If a person has a history of positive tuberculin skin test, another test is not necessary.

The results of this test should be interpreted carefully. The medical risk factors of the person to determine what size in millimeters of induration the result is positive ( 5 mm , 10 mm or 15 mm ). A positive result indicates TB infection (commonly abbreviated to “TB”).

5 mm or more is positive in people


having had recent contact with TB,

with nodular or fibrotic changes on chest radiographs that are consistent with previously treated tuberculosis,

transplanted organ or other patients immunocompromised

10 mm or more is positive in people

Recent arrivals (less than 5 years) from countries where the disease is endemic,

injection drug users,

resident or employed in high-risk environments (eg, prisons, nursing homes, hospitals, homeless shelters,  etc.. )

Mycobacteriology laboratory personnel,

people in clinical conditions as they are classified as high risk (eg, diabetes , prolonged therapy with corticosteroids , leukemia , kidney failure , chronic syndrome of malabsorption , body weight down  . etc. )

children less than 4 years, or children and adolescents exposed to adults in high-risk categories.

15 mm or more is positive in people

with no known risk factor for TB,


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