History of TB infection

Mycobacterium tuberculosis is the bacterium that causes History of TB infection tuberculosis (TB) is present in the human population since antiquity – from 2400 BC show clear signs of tuberculosis of the spine fragments of Egyptian mummies.

The term “consumption”, consumption, appears first in Greek literature. Around 460 BC, Hippocrates identified phthisis as disseminated disease at the time, and concluded that it is almost always fatal. Deaths, thanks joint tuberculosis, he wrote something that no doctor would dare write today: he warned his colleagues before visiting TB patients in advanced stages of the disease, because their inevitable death could damage the reputation of the physicians.

History of TB infection

Accurate pathological and anatomical descriptions of the disease began in the seventeenth century appears. In his Opera Medica 1679, was the first to identify actual tubercles Sylvius as a constant and characteristic change in the lungs and other areas of consumption patients. He also described the progression of abscesses and cavities. The first references to the infectious nature of the disease appear in the Italian literature of the seventeenth century. An edict of the Republic of Lucca in 1699 reported that “henceforth, human health is not compromised by more objects after the death of a remaining consumer. Names of the deceased must be reported to the authorities and led to out disinfection measures. ”
Tuberculosis caused victims is well aware of the history of mankind. Reached epidemic proportions in Europe and North America in the 18th and 19th century, earning the nickname “Captain Of these men of death.” Then it began to decline. The understanding of the pathogenesis of tuberculosis began with the work of Théophile Laennec early 19th century and was demonstrating the portability of Mycobacterium tuberculosis by Jean-Antoine Villemin in 1865 and identification of Mycobacterium tuberculosis by Robert Koch in extended 1882 Clemens von Pirquet agent developed the tuberculin test in 1907 and three years later used to demonstrate latent tuberculosis infection in asymptomatic children. In the late 20th century sanatoriums 19th and early treatment of patients with tuberculosis developed. The remaining wine developed lung collapse process adds to the recovery of infected lungs and closing parts cavities. Public health measures to combat the spread of tuberculosis was after the discovery of the bacterial cause. The BCG vaccine was well after the Second World War, the modern era of tuberculosis treatment and control was the discovery of streptomycin in 1944 and 1952 marked isoniazid busy.
Also according to the development of advanced detection methods of diagnosis and treatment for the disease, a third of the world population has been exposed ae infected body. The numbers are higher than 90% in developing countries.
With the advent of HIV infection, there is a worrying resurgence of TB with more than 8 million new cases worldwide each year more than 2 million people die. In the nineteenth century, TB was known as “the captain of the men of death.” History of TB infection This applies especially today.


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