EBV Test, Is it important?
November 10, 2016
EBV Test is a laboratory test to check if someone have ever got infected by Epstein Barr Virus or not. The test is using EBV antibodies. It detects the presence of EBV antibody in your body. What is the principle?
Antibodies are the proteins that produced by your immune systems to against the harmful substance from outside of your body, called antigen. Everytime, certain antigen attack our body, our immune system will produce certain antibody to protect our body. Sometimes it win, but sometimes it can lose to against the antigen. When Epstein Barr virus infect our body, our B lymphosite will produce several antibody. There are three antibodies that can be detected after the infection. Viral Capsid antigen (VCA) IgG, VCA IgM, and Epstein Barr nuclear antigen (EBNA). These are what EBV test will detect.
The presence of these antibodies will live at long time. So, the result of EBV test is not always about current infection. Perhaps the infection has happened at previous year, and it is still detected. If you want to know the about the current infection, you can see only from one indicator. That is, VCA IgM antibodies are present and antibody to EBNA are absence. Antibody to EBNA will develop after 6 to 8 weeks after the first time of infection.
According to Boston studies, almost 95 of all people over the world have got infected by EBV. It infect in silent condition, because no symptoms or just mild symptoms show up when the infection happened. So people always don’t notice about this. So, sometimes, this EBV test is questioned. Is this important thing to perform or not.
EBV test, how to perform?
EBV test is a blood test. The method to take sample is similar with other blood test when you want to do medical check up. Blood is drawn from your vein, usually from elbow. Unfortunately, at first time, very little antibodies is available in early days of infection. So, sometimes you need to repeat the blood test after 10 to 14 days.